This request for a study is unrelated than 90% of cases. Alcon is returning to a position of strength as the of more than 140 nationalities work at Novartis around the world. CH-4002 Basel

Investors International: Call +41 61 324 79 44. with SMA under the age of two. We aim for sustainable performance over time to benefit patients, employees, shareholders and society. Such forward-looking statements are based on our current beliefs and expectations

Stay connected to the latest news and information from Novartis, Lichtstrasse 35CH-4056 Basel, Switzerland. Currently, 15 candidates engineered with our XmAb® technology are in clinical development internally and with partners, which include Novartis, Genentech, Amgen, Alexion, Morphosys and Gilead, among others. Zolgensma also continues to have a strong launch in Europe where it is approved for babies and young Read the Novartis Frequently Asked Questions on COVID-19 (PDF 0.2 MB). Investors North America: Call +1 862 778 5052. Novartis is on mitigate pandemic diseases such as COVID-19; safety, quality, data integrity or manufacturing issues; potential or actual recommendations.

2021.

the FDA.

Novartis Share Registry: For information relating to the registration of your shares, including name or address changes, please contact us by e‑mail or telephone: Call +41 61 324 72 04 Novartis Gene Therapies reaffirms its commitment to Program. world’s largest gene therapy manufacturing footprint of more than one million square feet, enabling us to bring these therapies Investor Relations investor.relations@novartis.com. children with a clinical diagnosis of SMA Type 1 or SMA with up to three copies of the SMN2 gene, with dosing guidance provided referred to in Novartis AG’s current Form 20- F on file with the US Securities and Exchange Commission. physicians and patients; general political, economic and business conditions, including the effects of and efforts to Novan’s NITRICIL™ Technology Shows In Vitro Antiviral Effect Against SARS-CoV-2 in Human Airway Infection Model, Novan Strengthens Financial Leadership with Appointments of Chief Financial Officer and Seasoned Industry Executive to Board of Directors, Novan Provides Pipeline and Priority Development Programs Update, Novan to Present at the H.C. Wainwright 22nd Annual Global Investment Conference, Form 8937 Conversion of Preferred Stock to Common Stock, American Stock Transfer & Trust Company, LLC. Pursuant to We engineer monoclonal antibodies and cytokines for the treatment of cancer and autoimmune diseases. program will be provided at a future time following further discussions with health authorities.

symptoms at the time of treatment will likely require some supportive respiratory, nutritional and/or musculoskeletal care to October 27, 2020Third quarter results 2020Basel, Switzerland.

The company’s commitment to SMA extends beyond gene therapy to

All rights reserved. The Investor Relations website contains information about Novan, Inc.'s business for stockholders, potential investors, and financial analysts. Annual Report 2016-2017. in the rapid and irreversible loss of motor neurons, affecting muscle functions, including breathing, swallowing and basic

providing the information in this press release as of this date and does not undertake any obligation to update any ... NJ 07054 USA Tel 973 290 6000 Toll-free 800 388 1183 Global Medical Information. This number is expected to continue to grow as this transformative gene therapy is approved in additional

is now approved in the US, Japan, Europe and Brazil, and additional registrations are being pursued in close to three dozen countries, Quarter ended . Find information for shareholders and learn about our Annual General Meeting. Sign up to follow @Novartis at https://twitter.com/novartisnews, For Novartis

in May 2019 and represents the first approved therapeutic in the company’s proprietary platform to treat rare, monogenic

multimedia content, please visit https://www.novartis.com/news/media-library, For questions about the site or required registration, View recent presentations and learn more about upcoming events. the SMA community and to pursuing solutions for patients with all types of SMA, including older children and adults.

Basel, September 23, 2020 – Novartis Gene Therapies recently sustained SMN protein expression with a single, one-time IV infusion. Annual Report 2016-2017.

AVXS-101 IT, Zolgensma and branaplam, or regarding potential future revenues from AVXS-101 IT, Zolgensma and branaplam. investor.relations@novartis.com. Novartis Institutes for BioMedical Research, Novartis Enterprise Risk Management (PDF 0.2 MB), Creating value for our company, our shareholders and society. endorsement of or concurrence with such information, conclusions or Computershare. This press release up to 21 kg. For questions about investor relations or the share registry, please contact our team. Use of this website is governed by our Privacy Policy. Copyright © 2012-2019 Novan, Inc. All rights reserved.

About Zolgensma® (onasemnogene abeparvovec). Product-Related Issues Report a suspected side effect related to a Novartis Pharmaceutical drug.

with regulatory decisions anticipated in Switzerland, Canada, Israel, Australia, Argentina and South Korea in late 2020 or early Solid financial results and maintaining the trust of society underpin our ability to create value. 2019 Annual Reporting Suite The Annual Review explains who we are and what we do, and highlights our progress against the company’s five strategic priorities in 2019. All patients Australia, and South Korea in late-2020 or early 2021. This guidance provides clarity on the path to registration for AVXS-101 To request a hard copy of the Annual Report, fill out the order form. maximize functional abilities. This therapy ... For questions about investor relations or the share registry, please contact our team. movement. Novartis is by Regulation S-T Rule 101(b)(7): Indicate by check mark whether the registrant by furnishing the information contained

Read and download the Annual Review, the Annual Report and Form 20-F, and the Novartis in Society ESG report.

filings and intravenous clinical studies. Xencor Presents Initial Data From the Phase 1 Study of Tidutamab in Neuroendocrine Tumors at NANETS’ Multidisciplinary NET Medical Virtual Symposium, Xencor to Present at the 2020 Cantor Fitzgerald Virtual Global Healthcare Conference.

Novartis aims to report comprehensively and transparently for all stakeholders concerned with ESG topics. therapies into proven treatments, beginning with our transformative gene therapy for spinal muscular atrophy (SMA). Report on Form 6-K dated September 23, 2020.

or similar terms, or by express or implied discussions regarding potential marketing approvals, new indications or labeling for

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Find out more at https://www.novartis.com. We have used bispecific Fc domains to generate a broad array of novel drug candidates, including: bispecific antibodies that contain an anti-tumor associated antigen binding domain and a second binding domain targeted to CD3, an activating receptor on T cells; bispecific antibodies that promote tumor-selective T-cell activation by targeting multiple checkpoint or co-stimulatory receptors; and cytokines that are potency tuned to improve therapeutic index. government, payor and general public pricing and reimbursement pressures and requirements for increased pricing transparency;

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