The NIAMS Extramural Program supports research supports research via grants and contracts in the Division of Extramural Research. An important area of research for the Branch includes investigation of the skin microbiome in health and disease. August 1950—An arthritis program was established within the National Institute of Arthritis and Metabolic Diseases under Public Law 81-692. The Branch focuses on the TNF-family of cytokines and their receptors, from basic investigation of the trafficking and signaling by these molecules to the study of human diseases involving TNF-family cytokines and their receptors.

Areas of particular emphasis include: investigations of stem cells found in skin; studies related to wound healing and fibrosis; heritable disorders of connective tissue (such as Marfan’s syndrome); studies related to itch; metabolic studies of skin, such as the effects of hormones and the role of enzymes in skin barrier formation; and immunologically mediated cutaneous disorders, such as atopic dermatitis, contact dermatitis, and vasculitis. 11001 0 obj <> endobj The Intramural Research Program of the NIAMS conducts innovative basic, translational, and clinical research relevant to the health concerns of the Institute and provides training for investigators interested in careers in these areas. October 2000—The Children's Health Act of 2000 (P.L. April 1976—After a year of study and public hearings, the commission issued a comprehensive plan aimed at diminishing the physical, economic, and psychosocial effects of arthritis and musculoskeletal diseases. %%EOF The programs comprising Skin Biology and Diseases support a broad portfolio of basic, translational, and clinical research in skin. The National Incident Management System guideline for mutual aid helps with mutual aid planning and shows how to create legal agreements with others that include common practices and processes.

The program works closely with the NIH Clinical Center, and has established an ongoing collaboration with the international NIH-funded Vasculitis Clinical Research Consortium. Skin Biology and Diseases. Led by the NIAMS, the NIH Rheumatology Training Program is two years in duration, with extensions available for individuals interested in advanced research training as NIAMS Scholars in Translational Medicine. He was the principal investigator (PI) of the NIAMS-supported UAB Rheumatic Disease Core Center and the PI of an Autoimmunity Center of Excellence supported by the National Institute of Allergy and Infectious Disease (NIAID). Using an approach that integrates genomics, bioinformatics, and mechanistic investigations, the program aims to identify the causes of genetically complex autoinflammatory diseases, including systemic juvenile idiopathic arthritis and Behçet’s disease. November 20, 1985—The Health Research Extension Act of 1985 (P.L. The goal is to provide clinical insights into conditions that cannot be examined in traditional clinical studies. As Deputy Director, Dr. Carter led NIAMS policy initiatives and projects such as the NIAMS Centers Evaluation Working Group and Clinical Trials Working Group. September 1993—The NIH Revitalization Act of 1993 (P.L. Your community risk assessment will identify potential shortfalls and capability gaps that a mutual aid agreement can help to address. The technology development component includes methods for imaging bone and cartilage to improve the diagnosis and treatment of skeletal disorders, or to facilitate the repair of damage caused by trauma to otherwise healthy musculoskeletal tissues including bone, cartilage, tendon, ligament, intervertebral disc, and meniscus. The Branch enables NIAMS fellows to become leaders in the biomedical research community and provides trainees with a genuine growth experience, enhancing their ability to compete for independent research or other science-related careers in government or the private sector.

These efforts include work on the developmental and molecular biology of skin and skin appendages (such as the hair follicle), the study of skin as an immune organ, and the genetics of skin diseases. The NIAMS is committed to pursuing new opportunities in genetics and genomics research, clinical trial design, pain, and biopsychosocial aspects of diseases in this portfolio. 1982—The U.S. Department of Health and Human Services (HHS) conferred bureau status on the Institute, resulting in creation of the Division of Arthritis, Musculoskeletal, and Skin Diseases and the appointment of a division director. The Branch also aims to extend knowledge of interactions of immune cells in skin and skin appendage niches, combining mouse genetics, bioinformatics, immunology and cell biology. October 1976—The Arthritis, Diabetes, and Digestive Diseases Amendments of 1976 (P.L.

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